Mathematics, Natural Sciences and Technology

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Laboratory of Chemical Genomics at DSU

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Welcome to the home of The Laboratory of Chemical Genomics, located within the Department of Chemistry, on the main campus of the Delaware State University.   Photo: Dr. Eric Kmiec (front row, second from the left) is surrounded by members of his lab at a recent benefit awards ceremony. Dr. Kmiec's work in sickle cell disease has been recognized by several organizations, including the Proudford Foundation. View article here. Research in the Kmiec Laboratory For over twenty years, the Kmiec laboratory has studied the reaction mechanics, biochemistry and molecular genetics of gene editing in human cells. During the late 90s, this laboratory began a long-term investigation centered on understanding the mechanism and regulation of gene editing using single-stranded DNA oligonucleotides (ODNs). The lab was a pioneering force in developing the use of these specialized ODNs for the treatment of inherited disorders. Building largely on early genetic studies in lower eukaryotes, we were able to define a reaction protocol that can achieve a sustainable level of correction of genetic mutations in human cells. Development of clinical application is underway with a particular focus on utilizing nanofiber scaffolds as patches for implantation of gene edited cells into human tissues. For example, Phenylketonuria (PKU) is an amenable target for which nanofiber patches containing genetically modified cells can be implanted and the mutant phenotype reversed. These nanofiber scaffolds are constructed from natural biodegradable composite fibers, such as chitosan/PCC, created by electrospinning in both aligned and random configurations. Importantly, these patches enable robust proliferation of genetically modified cells. Since the nanofiber constructs are biodegradable, the 3D patchwork is slowly dissolved as the modified or gene corrected cells effectively implant in the target tissue. A major part of this effort centers on identifying chemical compositions of nanofibers that enable the greatest degree of expansion of cells that have been altered by the gene editing protocol. The laboratory is also investigating related reaction barriers including a reduced growth potential and the frequency at which gene editing activity takes place. The ultimate goal of all of this translational research is to develop a feasible protocol for the delivery of genetically modified cells into human tissues using biodegradable nanofiber patches. Back to Chemistry Department home page Back to College home page
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A Message from Dean

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A Message from the Dean       Welcome to the website of the College of Mathematics, Natural Sciences and Technology (CMNST), home of the Departments of Mathematical Sciences, Biological Sciences, Physics and Pre-Engineering, Chemistry, Computer and Information Sciences and the Army & Air Force Reserve Officer’s Training Corps.   CMNST offers a wide range of Baccalaureate, Masters and Doctoral degree programs. These are periodically reviewed to ensure that they remain strong, viable and relevant. CMNST is also the home of excellent research programs in areas such as atomic, molecular and optical physics, forensic science, neurosciences, data mining, applied mathematics and applied chemistry.  Mathematics, Natural Sciences and Technology play a critical role in many aspects of our lives and have proven to be a powerful engine for economic growth. These fields better prepare students to meet the rigor required to better understand the world around and are essential to strengthen our ability to Innovate, which, together, yield opportunities to enrich the lives of many citizens. Our college strives to provide a rich, stimulating and supportive environment in which students, faculty and staff work and study. To better prepare our students to meet the challenges of the 21st century, we provide programs and mechanisms so that students can learn fundamentals in the classroom and be engaged in various research activities in laboratories, working alongside energetic and dedicated faculty. CMNST is committed to offer opportunities for inspired and engaged teaching in an academic setting that puts students first. If you wish to talk to a faculty member, visit our laboratories, and/or join us as an undergraduate or graduate student, please feel free to contact us at 302.857.6500 or by email at CMNSTinfo@desu.edu. Thank you for visiting our website. I wish you much success and hope to see you on our campus soon.   - Noureddine Melikechi, D. Phil., Professor of Physics and Dean   Back to College Home Page

Research

Research Interest

  •  Fractional Calculus
  •  Combinatorics
  •  Computer Science - Data Compression Techniques
  •  Numerical methods for ODE, PDE and SDE
  •  Control Theory
  •  Image Processing
  •  Mathematical Biology

Publications

Publications

  1. New Approach To A Generalized Fractional Integral, Applied Mathematics and Computation, Vol 218, Issue 3, p 860-865, 2011.  (Access)

Boukari Webpage

Education:
  • Ph.D 1992: Chemical Physics, University of Maryland, College Park, Maryland.
  • M.Sc 1986: Chemical Physics, University of Maryland, College Park, Maryland.
  • Diplome d'Etudes Superieures 1983: Universite d'Annaba, Annaba, Algeria.

 

Research Interests:

Dr. Udita Katugampola

Udita Katugampola

Assistant Professor of Mathematics
Department of Mathematical Sciences
Delaware State University
Dover, DE 19901
Tel: (302) 857-7901
Email: udita@desu.edu

Szabo-Maas Lab

Studies in systems ranging from humans to lower vertebrates have demonstrated that neural circuits can be modulated by steroid hormones. Many organs in the body are receptive to steroid hormones, which exert their actions either indirectly via the circulation or directly via local production in tissues, including the brain.

Dr. Jinjie Liu

Jinjie Liu

Assistant Professor of Mathematics and Director of Math Graduate Program,
Department of Mathematical Sciences,
Delaware State University
Dover, DE 19901
Office: (302) 857-7041
Email: jliu at desu dot edu

 

Mathematics Preparation Program

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Mathematics Preparation Program   Sponsored by the College of Mathematics, Natural Sciences, and Technology   FOR INCOMING FRESHMEN AND HIGH SCHOOL STUDENTS: Get a head start!  Register for MP2 and get the support you need to be successful in college.   As an incoming freshman or high school student, you are eligible to register for the Mathematics Preparation Program (MP2) before you officially begin your college career. MP2 offers two summer courses.  The first course is a mathematics course that will prepare students for college-level mathematics using research-supported, innovative mathematics teaching techniques and enrichment activities based on national and state standards.  The enrichment activities will help students build a solid foundation of fundamental mathematical concepts and procedures necessary for success in college mathematics courses and college courses with a quantitative reasoning emphasis.  Depending on placement during New Student Orientation, the mathematics course may earn credits towards graduation. The second course is an enhanced English Composition course. Students will build a solid foundation in grammar and professional writing techniques. Participants who successfully complete the English Composition I course will earn three (3) college credits towards graduation. Students attending the MP2 summer course will … Develop a more positive disposition regarding one’s capacity, confidence, and inclination to “do mathematics”; Develop a stronger understanding of rational numbers and operations involving rational numbers; Develop reasoning skills that are necessary for organizing one’s mathematical knowledge and applying that knowledge to novel problems; Develop sense-making skills to  successfully interpret mathematical definitions and contextualized problem situations; Demonstrate the ability to make generalizations to create mathematical rules, formulas, and equations; and Justify and debate mathematical arguments.   Program Options MP2 offers the convenience of flexible registration options.  See application for program cost and details. Option 1: Mathematics Course Only Option 2: Mathematics and English Composition I Option 3: Mathematics and English Composition, with On-campus Housing and Meal Plan.    MP2 Summer Course Information 6-week Summer Program on DSU Dover campus June 30, 2014 – August 8, 2014 First priority for incoming DSU freshman Summer housing option available Evening study sessions include tutoring Daily round trip transportation is NOT available Application deadlines… Option 1, 2, & 3 is June 2, 2014.   Option 3 unavailable after June 2, 2014. Applications for Options 1 & 2 will be accepted after the deadline if space is available. Space is limited, so apply early. Installment payment plans available. See application for details.
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Application

Brochure

 

For more information contact:

The Department of Mathematical Sciences
1200 North DuPont Hwy
Dover, DE 19901
Phone: 302-857-7051
Fax: 302-857-7054
E-mail: mp2@desu.edu
 
 
MP2 Program Director
Dr. Nicola Edwards-Omolewa
Phone: 302-857-6645
 

Model of Mars Rover, Curiosity, on display at DSU

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In search of signs of previous life... NASA's next Mars rover, Curiosity, is slated to land on the Red Planet on Aug. 6, 2012 (EDT). Watch a real-time visualization of its journey through space and get up-to-date data sets using NASA's Eyes on the Solar System 3-D interactive. (Free browser plug-in required.)          Shown below is a picture of the 1/10 model of the Mars Rover, called Curiosity, that will be on display at Delaware State University for 10 days, through May 2nd.                     Dr. Noureddine Melikechi (pictured below with his team), a DSU Physics research scientist, inventor, Vice President for Research and Dean of the College of Mathematics, Natural Sciences & Technology, leads a team of DSU scientists who play an important role on the Curiosity mission to Mars. They help create the instrumentation that is being carried on the Curiosity and help interpret the data that is transmitted to Earth by the rover. Find out more about DSU and the Curiosity Mars Rover mission.

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